reversal of autismlike behaviours
Wednesday 15 January 2025
Last Updated : GMT 09:40:38
Themuslimchronicle, themuslimchronicle

New study on mice

Reversal of Autism-like behaviours

Themuslimchronicle, themuslimchronicle

Themuslimchronicle, themuslimchronicleReversal of Autism-like behaviours

Crucial link between protein and autism spectrum disorders
London - Arabstoday

Crucial link between protein and autism spectrum disorders London - Arabstoday Researchers from McGill University and the University of Montreal have identified a crucial link between protein synthesis and autism spectrum disorders (ASD), which can bolster new therapeutic avenues. Protein synthesis, also termed mRNA translation, is the process by which cells manufacture proteins. A new study in mice has found that abnormally high synthesis of a group of neuronal proteins called neuroligins results in symptoms similar to those diagnosed in ASD. The study also reveals that autism-like behaviors can be rectified in adult mice with compounds inhibiting protein synthesis, or with gene-therapy targeting neuroligins. Professor Nahum Sonenberg, from McGill’s Dept. of Biochemistry, Faculty of Medicine, and the Goodman Cancer Research Centre said: \"Our team was surprised to discover that similar mechanisms may be implicated in the development of ASD. We used a mouse model in which a key gene controlling initiation of protein synthesis was deleted. In these mice, production of neuroligins was increased.\" Autism spectrum disorders (ASD) encompass a wide array of neurodevelopmental diseases that affect three areas of behaviour: social interactions, communication and repetitive interests or behaviors. Computer modeling played an important role in this research. Professor François Major, of the University of Montreal’s Institute for Research in Immunology and Cancer said: “By using a new sophisticated computer algorithm that we specially developed to answer Dr. Sonenberg\'s questions, we identified the unique structures of mRNAs of the neuroligins that could be responsible for their specific regulation.” The researchers found that dysregulated synthesis of neuroligins augments synaptic activity, resulting in an imbalance between excitation and inhibition in single brain cells, opening up exciting new avenues for research that may unlock the secrets of autism. This research was funded by grants from the Canadian Institutes of Health Research (CIHR), the Autism Speaks Agency and the Fonds de la recherche du Québec – Santé.

themuslimchronicle
themuslimchronicle

GMT 08:21 2018 Tuesday ,23 January

Saudi-led coalition announces $1.5bn

GMT 08:05 2018 Monday ,22 January

UN appeals for nearly $3 bn to save

GMT 07:39 2018 Sunday ,21 January

Second face transplant for Frenchman

GMT 11:20 2018 Saturday ,20 January

China sees births fall despite push

GMT 06:43 2018 Friday ,19 January

Police raid France's Lactalis

GMT 06:21 2018 Thursday ,18 January

Suppressing a sneeze can be dangerous

GMT 07:42 2018 Wednesday ,17 January

Populists target vaccine decree

GMT 07:37 2018 Tuesday ,16 January

Lactalis feels heat as families rebuff
Themuslimchronicle, themuslimchronicle
Themuslimchronicle, themuslimchronicle

Name *

E-mail *

Comment Title*

Comment *

: Characters Left

Mandatory *

Terms of use

Publishing Terms: Not to offend the author, or to persons or sanctities or attacking religions or divine self. And stay away from sectarian and racial incitement and insults.

I agree with the Terms of Use

Security Code*

reversal of autismlike behaviours reversal of autismlike behaviours

 



Themuslimchronicle, themuslimchronicle
Themuslimchronicle, themuslimchronicle
Themuslimchronicle, themuslimchronicle

GMT 11:11 2017 Tuesday ,12 December

Jordan referred to UN for not detaining Sudan leader

GMT 18:07 2017 Wednesday ,04 October

Nadal dodges upset ax in Beijing

GMT 11:39 2017 Monday ,04 December

Houthi tanks storm Sana'a streets to raise chaose

GMT 15:16 2017 Thursday ,14 December

EU agrees increases in fishing quotas

GMT 08:14 2017 Tuesday ,14 March

Damages pristine Indonesian coral reef

GMT 13:14 2011 Friday ,16 December

Dell says goodbye to Netbooks

GMT 22:18 2012 Monday ,09 January

Players

GMT 20:34 2011 Thursday ,25 August

Gods Without Men

GMT 12:46 2017 Friday ,31 March

National Skills Contest concludes

GMT 18:26 2011 Monday ,25 April

North Korea visit to focus on food crisis

GMT 14:49 2014 Saturday ,11 October

Meetings with IMF going on normally

GMT 21:39 2014 Friday ,03 October

Intensified campaigns launched to control markets

GMT 09:08 2017 Thursday ,19 October

California fire toll rises to 42
Themuslimchronicle, themuslimchronicle
Themuslimchronicle, themuslimchronicle
 
 Themuslimchronicle Facebook,themuslimchronicle facebook  Themuslimchronicle Twitter,themuslimchronicle twitter Themuslimchronicle Rss,themuslimchronicle rss  Themuslimchronicle Youtube,themuslimchronicle youtube  Themuslimchronicle Youtube,themuslimchronicle youtube

Maintained and developed by Arabs Today Group SAL.
All rights reserved to Arab Today Media Group 2023 ©

Maintained and developed by Arabs Today Group SAL.
All rights reserved to Arab Today Media Group 2023 ©

muslimchronicle muslimchronicle muslimchronicle muslimchronicle
themuslimchronicle themuslimchronicle themuslimchronicle
themuslimchronicle
بناية النخيل - رأس النبع _ خلف السفارة الفرنسية _بيروت - لبنان
themuslimchronicle, themuslimchronicle, themuslimchronicle