University of Michigan researchers have used a "kidney on a chip" device to mimic the flow of medication through human kidneys and measure its effect on kidney cells. 
The most significant impact of the research is providing a better understanding of how to safely administer drugs. 
The new technique could lead to more precise dosing of drugs, including some potentially toxic medicines often delivered in intensive care units, according to ScienceDaily website. 
The new technique offers a more accurate way to test medications, closely replicating the environment inside a human kidney. It uses a microfluidic chip device to deliver a precise flow of medication across cultured kidney cells. 
A kidney on a chip enables us to simulate that filtering process, providing a much more accurate way to study how medications behave in the body. 
The techniques used in the study should be generalizable to a wide variety of other organs and medications, enabling researchers to gather detailed information on how medications affect the heart, liver and other organs.

Source: QNA